By Denham M.C., Whittaker J.

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This group is heterogeneous that shows oncocytoid features. • Allelic imbalances occur at the 20q13 locus. The prognosis is similar to other RCC. Uni- or bilateral lesions develop at mean age of 13 years. 10 RCC with Sarcomatoid or Rhabdoid Differentiation • Current WHO classification does not consider sarcomatoid RCC as an entity but rather as a progression of any RCC main type. Pure sarcomatoid morphology without recognizable epithelial elements falls into the unclassified RCC category (Figs.

55 High power view of image Fig. 54 Fig. 1 Medullary Fibroma • Also known as renomedullary interstitial cell tumor. These tumors are frequently multiple and found incidentally at autopsy or surgery for another condition. 5 cm (Fig. 57). • The cells are small stellate, spindle or polygonal in a loose basophilic stroma and seems to originate from prostaglandin-producing interstitial cells in renal medulla. Tubules maybe entrapped at the periphery. Amyloid deposits may be present. 1 38 Renal Tumors and Tumor-Like Conditions Fig.

Osteosarcoma-like areas occurring in sarcomatoid carcinoma are more frequent than primary renal osteosarcoma, and therefore, sarcomatoid carcinoma should always been excluded. 20 Other Soft Tissue Tumors • Extremely rare examples of chondrosarcoma, mesenchymal chondrosarcoma, malignant schwannoma, malignant mesenchymoma, clear cell sarcoma of the soft parts, low-grade fibromyxoid sarcoma of the renal capsule, and cystic embrional sarcoma, originating in the kidney have been reported. 5 months) Renal Tumors and Tumor-Like Conditions comatoid carcinoma may morphologically mimic virtually all sarcoma histotypes.

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A Bayesian approach to disease gene location using allelic association (2003)(en)(11s) by Denham M.C., Whittaker J.

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